Other variables, including age, gender, active smoker, alcohol drinking, duration of HF, HF aetiology, maintained dose of sacubitril/valsartan, history of ischaemic heart disease, hypertension, or stroke, use of digoxin, anticoagulants, statins, P2Y12 antagonists, and amiodarone, systolic blood pressure (SBP), diastolic blood pressure (DBP), laboratory tests, echocardiography data, and loop diuretics dose were similar between Group A and Group B. This evidence concerns the gene P2RY12 and hydrops fetalis.