Streptozotocin-induced T1DM shows a protective effect in AAA induced by either by elastase infusion in the abdominal aorta of C57BL/6 mice or by Angiotensin II (Ang II) infusion in apolipoprotein E knock-out (ApoE−/−) mice (33, 34). The gene discussed is APOE; the disease is type 1 diabetes mellitus.