Analysis of inflammatory markers in serum and/or CSF of neurosarcoidosis patients showed elevated levels of neopterin in CSF or serum in 19/22 (86.4%) patients, elevated levels of sIL-2R in CSF or serum (16/25, 64.0%), elevated serum TNF-α (10/19, 52.6%), elevated serum β2 microglobulin (4/8, 50.0%), elevated serum IL-6 (8/18, 44.4%%), elevated serum ACE (6/20, 30.0%) and elevated serum CRP (8/27, 29.6%) in descending order, while no patient showed elevated levels of IL-1β (0/14, 0.0%) (Table 2). This evidence concerns the gene TNF and neurosarcoidosis.