Jaafar F et al. reported a case of anti-GAD encephalitis that developed into super-refractory SE and was unresponsive to a combination of conventional ASMs; intravenous immunoglobulin (IVIG), high doses of corticosteroids and plasma replacement therapy were partially effective, but golimumab and ketogenic diet showed significant improvement in clinical symptoms. The gene discussed is GAD1; the disease is encephalitis.