CTNNB1 and familial pancreatic carcinoma: Additionally, CTNNB1 had the highest deep deletion rate across pan-cancer at 5%, followed by TGFB1 at 3.6% in head and neck cancer and 2.2% in non-small cell lung cancer, and TNF and PPARG in pancreatic cancer with rates of 3.6% and 1.3%, respectively, (Figure 5C).