METTL5 and posterior cortical atrophy: By comparing the expression of m6A-related genes in prostate normal cell line (RWPE-1) and 2 PCa cell lines (22Rv1 and PC3), 8 significantly DEGs were screened out by RT-qPCR, among which METTL3, ALKBH5 and hnRNPA2B1 were highly expressed in PCa cells, while METTL5, YTHDF1, IGF2BP2, IGF2BP3 and hnRNPC were lowly expressed in PCa cells (Figure 14A).