By comparing the expression of m6A-related genes in prostate normal cell line (RWPE-1) and 2 PCa cell lines (22Rv1 and PC3), 8 significantly DEGs were screened out by RT-qPCR, among which METTL3, ALKBH5 and hnRNPA2B1 were highly expressed in PCa cells, while METTL5, YTHDF1, IGF2BP2, IGF2BP3 and hnRNPC were lowly expressed in PCa cells (Figure 14A). Here, METTL3 is linked to posterior cortical atrophy.