We therefore compared the expression of the genes mediating cytokine storm in our patient cohorts and observed that, compared to individuals with mild COVID-19, patients with severe illness showed a significant increase in IL6, IFNG, IL18, and IL1B, while dexamethasone treatment decreased the abundance of IL6, IFNG and IL18 (Figures 3A, B) (30). Here, IFNG is linked to COVID-19.