ACTA1 and neoplasm: myCAFs were distributed in the periglandular region at a closer distance from tumor cells, with high expression of α-smooth muscle actin (α-SMA) and low expression of interleukin (IL)-6, whereas iCAFs were distributed more distantly throughout the tumor, with low expression of α-SMA but high expression of cytokines such as IL-6, IL-11, and leukemia inhibitory factor (LIF) (21).