Consequently, this leads to increased expansion of memory T cells, which predispose CD300f-/- mice to develop a systemic lupus erythematosus-like autoimmune disease when exposed to an overload of apoptotic cells, or an exacerbated autoimmunity when combined with FcγRIIB deficiency (8). The gene discussed is FCGR2B; the disease is Autoimmunity.