TLR3 and endometriosis: They tested the mRNA expression levels of a few selected genes involved in specific signaling pathways (TICAM, NF-κB1A, CXCL10, IRF3, IFN-B1, IL-6, and IL-8) in clinical specimens, to ascertain whether or not the elevated expression of TLR3 gene transcript in the endometriosis tissues resulted in a shift in the expression of downstream signaling molecules (81).