Tripartite motif 24 ubiquitinated NLRP3, and its absence increased the activity of the NLRP3/Caspase-1/IL-1β-mediated pyroptosis signaling, which was suggested as the mechanism by which human endometrial stromal cells (hESCs) migrated and released the pro-inflammatory cytokines IL-1β and IL-18, promoting endometriosis (124). Here, NLRP3 is linked to endometriosis.