Figure 3F showed the expression of six key genes. In addition, similar results were obtained in GSE72094 (Figures 3G–I). The qRT-PCR showed that a high expression of CPS1, HMGA2, and SLC39A11 was found in tumor compared with adjacent normal tissues by 16 paired LUAD samples from our center, while the expression of ABCC8, HVCN1, and MT1A was lower in tumor (Figure 3J). Here, CPS1 is linked to neoplasm.