Although the number of RCTs on dietary polyphenols is limited, existing evidence shows their potential benefits, mainly increasing DAS28, reducing CRP and ESR, and improving oxidative stress, etc. However, given the small number of patients recruited, the study designs varied widely between RCTs and the characteristics of RA patients varied; it is difficult to immediately extrapolate these results to RA patients in general. Here, CRP is linked to rheumatoid arthritis.