CD4 and neoplasm: The effect of DC-based vaccines on the increased tumor infiltration by effector immune cells was also reflected in the size of NKT cell and CD4+ T cell subpopulations, however, only in HES-MTX + DC/TAg and HES-MTX + DC/shIL-10R/TAg groups these alterations were statistically significant when compared to control (nt) group (Figures 4D, E).