In the case of lymphoid cell subpopulation infiltrating into tumor tissue, the size of CD8 (CD45+CD3+CD8+), NK (CD45+CD49b+), NKT (CD45+CD3+CD49b+) and CD4 (CD45+CD3+CD4+) cells among leukocytes in the tumor were determined, according to the scheme presented on Figure 4A. The gene discussed is CD4; the disease is neoplasm.