5 proteins (C1QC, C4B, FGB, FGG, and SERPINA1) were highly increased in the MN subgroup, while 13 proteins (C1QB, C3, C4A, C4B, C6, C8B, C8G, C9, F9, FGB, FGG, KNG1, and SERPINA1) were markedly increased in the LN subgroup. The gene discussed is C4A; the disease is lobular neoplasia.