According to our results, URB2 is significantly correlated with several immune checkpoint molecules in GBM, such as ADORA2A, BTNL2, CD160, CD200R1, and CD244, while the correlated immune checkpoint molecules in LGG include ADORA2A, BTLA, CD160, CD200R1, and CD27 (Figure 8E). This evidence concerns the gene BTLA and glioblastoma.