After the administration of a personalized vaccine generated by autologous DCs pulsed with oxidized autologous whole-tumor cell lysate (OCDC), an increase in IFN-γ-producing T-cell responsive to DC-presented tumor antigens was detected, with a significantly higher 2-year OS in patients who responded to the vaccine than in those who did not (100% vs 25%) and with good tolerability (Tanyi et al., 2018). Here, IFNG is linked to neoplasm.