NFKB1 and inflammatory bowel disease: Cur has a variety of biological functions, such as anti-inflammatory, anti-cancer, anti-oxidation, and hypoglycemic, etc. A large number of studies have proved that Cur may be interacted with NF-κB, JAKs/STATs, MAPK, PPARγ and TRPV1 to treat IBD and slow down the progress of IBD (Karthikeyan et al., 2021).