PGC-1α PGC1α binds to CCAAT/enhancer binding protein β (CEBPB) to enhance CPT1A transcription, resulting in activation of FAO through PGC1α/CEBPB/CPT1A/FAO signaling axis, which can promote radiation resistance of nasopharyngeal carcinoma (NPC) (Du et al., 2019). The gene discussed is CEBPB; the disease is nasopharyngeal carcinoma.