VLDLR and parasitic infectious disease: Previously, curcumin was able to reduce the parasitemia in T. cruzi infected animals (Nagajyothi et al., 2013) which is explained by the inhibitory effect of curcumin at the transcription of low-density lipoprotein receptor (LDLr) (Yuan et al., 2008; Kang and Chen, 2009; Nagajyothi et al., 2013) as it is known that the T. cruzi utilizes these LDLr during its cellular invasion process (Nagajyothi et al., 2011).