Our results revealed that a significant negative correlation between CHD1L expression and NKT infiltration was found in BLCA, BRCA, CESC, COAD, HNSC, HNSC-HPV-, KIRC, KIRP, LUAD, MEOV, PRAD, SKCM, STAD, THYM, and UVM. The gene discussed is CHD1L; the disease is bladder transitional cell carcinoma.