TMEM100 and migraine disorder: In addition, based on the data showing that 95 and 74% of TMEM100-positive sensory neurons express CGRP in mice (Weng et al., 2015) and rats (Yu et al., 2019), respectively, and in view of CGRP’s crucial role in migraine (Dussor, 2019), it would be interesting to investigate whether TMEM100 contributes to migraine via regulating CGRP levels.