DUOXA1 and posterior cortical atrophy: The MSRPI consists of seven metabolic syndrome-related genes (MSRGs), including CSF3R, TMEM132A, STAB1, VIM, DUOXA1, PILRB, and SLC2A4. Of these MSRGs, abnormal colony-stimulating factor receptor (CSFR) expression plays an oncogenic role in many hematologic and solid tumors, such as nasopharyngeal, breast, and ovarian cancers (35–37), but its role in PCa remains unclear.