The translocation was accelerated by the treatment of TDZD-8 in DMSO-treated H9c2 cells (Figures 7A, C), whereas it was not changed by the treatment of TDZD-8 in TMG-treated H9c2 cells (Figures 7B, D), which is consistent with the data showing that the treatment of TDZD-8 restored cardiac function and cardiac hypertrophy in Ogt-Tg mice after TAC4W (Figures 4, 5). Here, OGT is linked to cardiac hypertrophy.