Fifteen core genes, DNAJB9, VPS53, SCGN, CMAS, RGS6, FASLG, ABHD10, ATRN, PLA2G2F, ITIH2, ROBO1, SGCG, SH3GL2, CNR1, and FOXN3, were identified as shared between NAFLD and T2D. This evidence concerns the gene CMAS and metabolic dysfunction-associated steatotic liver disease.