APOA1 and atherosclerosis: Specifically, these markers have been associated to atherosclerosis, immune and inflammatory responses, AST and ApoA-I levels, iron toxicity, intraocular pressure, and compositional changes in extracellular matrices, which is essential for axonal health and growth, and may lead to nerve fiber loss in neuropathic conditions (26, 40, 42, 52–57, 61–64).