GSEA revealed that CXCL9, CXCR3, and ITGAX could activate “hematopoietic cell lineage” and “cell adhesion molecules.” Studies have shown that cell adhesion molecules are involved in the proliferation, fusion, migration, and invasion of trophoblast during placenta formation [29], and the dysregulation of the expression of these molecules can easily lead to pathological placenta, which can cause various obstetric complications such as intrauterine growth restriction [30, 31], but the exact mechanism needs further research. Here, CXCR3 is linked to fetal growth restriction.