INS and major depressive disorder: Those who do not take insulin were less likely to score higher (worse) than those who do take insulin on mobility (OR = 0.7, 95% CI: 0.5–0.9, p < 0.01), pain/discomfort (OR = 0.8, 95% CI: 0.6–1.0, p < 0.05), and anxiety/depression (OR = 0.5, 95% CI: 0.4–0.70, p < 0.001) sub-scales.