For both markers of Covi‐FERON ELISA (OS and VS), significantly higher IFN‐γ concentrations were detected in the COVID‐19‐positive group than one in the negative group (median of 2.49 IU/mL and 0.02 IU/mL, for OS marker, respectively, and median of 1.83 IU/mL and 0.02 IU/mL, for VS marker, respectively). This evidence concerns the gene IFNG and COVID-19.