IL6 and spindle cell hemangioma: This study found that the hsCRP level of the subclinical hypothyroidism group was higher than that of the normal group of pregnant women, which was consistent with the high hsCRP level in patients with SCH indicated by the meta-analysis of Tellechea [26] TSH can increase the secretion of interleukin-6 (IL-6), the main inducer of CRP, by upregulating the promoter activity of the IL-6 gene and increasing the stability of its mRNA of Raychaudhuri et al. [27].