TARDBP and Alzheimer disease: In this work, we extend prior literature by interrogating plasma p-tau181 and p-tau217 in relation to common neuropathologic indices of AD, non-AD degenerative (i.e., Lewy bodies, TDP-43 and hippocampal sclerosis), and cerebrovascular conditions (i.e., infarcts, cerebral amyloid angiopathy (CAA), atherosclerosis and arteriolosclerosis).