Previous studies also support the role of CXCL8 in tumour progression: CXCL8 enhanced tumour proliferation rate, angiogenesis and the ability to metastasize [38, 39]; recruited granulocytes at the site of inflammation [40, 41]; and high concentrations of CXCL8 were connected to worse survival in CRC patients [41]. Here, CXCL8 is linked to colorectal carcinoma.