CXCL9 and melanoma: To specifically express CXCL9 and αPD-L1 in melanoma cells for recruiting T cells and unleashing their antimelanoma reactivity, we used the Tyr promoter responsible for melanin synthesis32 to construct the melanoma-specific coexpression plasmid of CXCL9 and αPD-L1 (pTyr-C9AP) (Supplementary Figure 1a).