IAPP and Alzheimer disease: The mean level of oligomerized amylin-Aβ is higher in brains within the fAD group than those in the sAD and non-AD groups (one-way ANOVA, p < 0.001 and p < 0.01, respectively Fig. 4A), consistent with similar relationships between the average amylin and Aβ levels in fAD compared to sAD and non-AD groups (Fig. 4, B and C).