Moreover, NDUFS1 (NADH:ubiquinone oxidoreductase 75 kDa Fe‐S protein 1) is another member of complex I, its mutations also correlated with various diseases such as diabetic cardiomyopathy, myocardial hypertrophy, schizophrenia, leukoencephalopathy, and Leigh syndrome.33, 34, 35, 36, 37. Here, NDUFS1 is linked to Leukoencephalopathy.