These results are mirrored in our platelet transcriptomics, where SLE subjects showed upregulation of interferon related genes (IFITM1, IFI27, RSAD2, IFIT3, LGALS3BP) and the most enriched for pathways amongst the differentially expressed genes were interferon gamma response and interferon alpha response. The gene discussed is IFIT3; the disease is systemic lupus erythematosus.