For the IDH mutant astrocytoma and oligodendroglioma, there are the other 5 intersected gene sets, including ALLOGRAFT_REJECTION, DNA_REPAIR, IL6_JAK_STAT3_SIGNALING, INTERFERON_ALPHA_RESPONSE, and INTERFERON_GAMMA_RESPONSE, which were mainly associated with increased inflammation (Fig. 4D). Here, IDH1 is linked to astrocytoma (excluding glioblastoma).