Univariate analysis for OS was performed and showed a significant difference in favor of tumors with Ki-67 ≤ 20% vs. > 20% (p 0.001), well-differentiated grade (G) 1, G2 vs. G3 or neuroendocrine carcinoma (NEC) (p < 0.001), and surgical vs. primary medical management (p 0.001). Here, MKI67 is linked to neuroendocrine carcinoma.