A total of 12 clinical factors [Age, AFP, Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), Platelet-to-lymphocyte ratio(PLR), Operation time, Maximum tumor diameter, Anatomical liver resection, Microvascular invasion (MVI), Differentiation, CNLC stage] were significantly different between groups before PSM (Table 1, all p < 0.05). The gene discussed is AFP; the disease is neoplasm.