NDUFB8 and COVID-19: However, under reduced oxygen saturation in the lung of COVID-19 patients, downregulation of genes encoding lipid uptake, FAO, and NADH oxidation (NDUFB8, NDUFA11, NDUFA13) was found in severe COVID(+) NKTs (Supplementary Fig. 8b,c) suggesting mitochondrial dysfunction in NKTs during SARS-CoV-2 infection.