Given increased mitophagy has been found in CD8+Tc from PBMCs (Fig. 2g) and BALFs (Supplementary Fig. 6a, c) of COVID-19 patients, we investigated whether treatment with mitophagy inhibitor mdivi-1 could enhance the cellular function of CD8+Tc and CD8+TM after activation with SARS-CoV-2 peptide megapool. The gene discussed is CD8A; the disease is COVID-19.