In the Middle group, the levels of IL-1b, IL-8 and MIP-1a in the adenoma group were much lower than those in the hyperplasia group, and only MIP-1b was significantly higher than that in the hyperplasia group, while in the Opposite group, the levels of statistically significant indexes like IL-1b, IL-8 and TGF-a were also higher in the Hyperplasia group than in the Adenoma group. This evidence concerns the gene IL1B and adenoma.