Identified endocrine, nutritional, and metabolic disorders with higher risk were malnutrition (1.57 [95% CI, 1.43–1.72]), fluid and electrolyte disorders (1.32 [95% CI, 1.23–1.41]), diabetes mellitus (1.27 [95% CI, 1.17–1.37]), and edema (1.23 [95% CI, 1.16–1.30]), coupled with higher use of glucagon, insulin, and metformin. The gene discussed is INS; the disease is diabetes mellitus.