However, KH-CB19 did not show any effect even at relatively high doses of 50 and 100 μM, indicating that NIH39 may be a promising anti-viral therapeutic to combat influenza A.83 As CLK1 was found to play a crucial role in influenza replication, screening of CLK1 inhibitors was carried out by a virtual docking program. This evidence concerns the gene CLK1 and influenza.