Based upon data provided by TCGA, CLK1 is significantly overexpressed in many cancer types, including cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), prostate adenocarcinoma (PRAD), rectum adenocarcinoma (READ) and stomach adenocarcinoma (STAD) (Fig. 5a). The gene discussed is CLK1; the disease is cancer.