Suppressing the NF2 gene in the ARID1A mutant background gave iPSCs a growth advantage and, although direct interaction of ARID1A and NF2 is not known, both proteins regulate pathways inhibiting oncogenic YAP/TAZ genes, and their double mutation causes hepatocellular carcinoma in mice (Chang et al., 2018; Patel et al., 2017). The gene discussed is NF2; the disease is hepatocellular carcinoma.