There have been only a few clinicalstudies to test the effect of bioactive peptides on obesity and diabetes.One study demonstrated that Chinese T2D patients, who received 13g of marine collagen peptides each day for 3 months, showed improvedglucose hemostasis and increase insulin sensitivity with a decreasein fasting insulin by 19.8%. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.