As shown in Table 1, increased expression of FN1 mRNA was positively correlated with smoking index, T classification, N classification and clinical stage (P = .028, P < .001, P = .001, and P < .001; respectively), but not with age, gender, drinking index, tumor location, tumor differentiation, tumor size and metastasis (P > .05). This evidence concerns the gene FN1 and neoplasm.