The lower the value, the poorer the immune response capability of the cells against the tumor.[40] Tumor patients are often in a state of immune imbalance, with reduced CD4+ T cells, decreased CD4+/CD8+, and cellular immune dysfunction.[41] In this study, we found that ginsenoside Rg3 combined with chemotherapy increased the levels of CD3+, CD4+, CD8+, CD4+/CD8+ in peripheral blood T lymphocyte subsets in NSCLC patients compared with chemotherapy alone. Here, CD8A is linked to neoplasm.