IL6 and rheumatic heart disease: Logistic regression analysis showed that the elevated Factor XI concentration (OR = 3.60, 95% CI: 1.218–10.637, P < .05), the elevated TF level (OR = 3.75, 95% CI: 1.251–11.244, P < .05), the elevated D-D level (OR = 3.92, 95% CI: 1.281–12.017, P < .05), the elevated IL-6 level (OR = 4.29, 95% CI: 1.413–13.068, P < .05), and the decreased miR-145 expression (OR = 4.01, 95% CI: 1.284–12.465, P < .05) were the independent risk factors for intracardiac thrombosis in the patients with RHD.