MAPK8 and brain infarction: Injecting miR-145 transfected endothelial progenitor cells into the cerebral infarction mouse model can promote the proliferation and migration of mouse endothelial progenitor cells and the recanalization of arterial thrombosis through Jun N-terminal kinase signaling pathway.[55] Further studies showed that the level of miR-145 was negatively correlated with the thrombus load reflecting coagulation activity.