ARPC5 and squamous cell lung carcinoma: In their study of the regulatory mechanisms of lung squamous cell carcinoma development, Moriya et al[58] found that the ARPC5 protein was highly expressed in lung squamous cell carcinoma compared with normal lung tissue and that the invasive and migratory abilities of PC10 cells could be significantly inhibited by downregulating ARPC5 gene expression in the cell line PC10.