ACTR2 and malignant choroid melanoma: Kumagai et al[60] used gene microarray analyses and other methods to find that the ARPC1B subunit of the Arp2/3 complex could be used as a predictive marker for the sensitivity of choroidal malignant melanoma to radiation therapy, and that the mechanism may be related to the regulation of actin polymerization by the Arp2/3 complex.