The authors attributed this effect to the downregulation of Th17 and IL-17+ γδ T cells, reduced IL-17 production, and enhanced protolerogenic IL-10 secretion.64 Similarly, a single-center study of liver transplant recipients identified a significant elevation of Th17/Treg ratio in patients undergoing acute allograft rejection compared with stable recipients and pretransplant levels.65 Notably, there was a significant correlation between serum IL-17 levels and Th17 cell frequency.65 Here, IL17A is linked to medical procedure.