ASGR1 and hepatocellular carcinoma: ASGPR, a liver‐specific lysosome‐targeting receptor, is the most common target for drug delivery systems owing to its high expression on HCC but low expression outside hepatocytes.[31] ASGPR has high specificity and affinity for galactose (Gal), galactosamine, and pullulan.[32] Therefore, these structures were selected as targeting ligands for ASGPR (Figure 3a).